The Challenges

TMVR poses new challenges in comparison with TAVI:

  • Robust anchoring of the valve to the native annulus

  • Implantation in a minimally invasive approach – transcatheter

  • Creation of a simple and safe procedure

  • Elimination of paravalvular leaks (PVL)

  • Elimination of Left Ventricular Outflow Tract (LVOT) obstruction

  • Minimization of disturbance to the cardiac structure

  • Large valve area and high work blood pressures

  • Valve prosthesis durability

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